Cryo-Fluorescence Tomography (CFT) is a novel, 3D approach to imaging drug distribution and protein expression in whole animals and large tissue samples. EMIT Imaging offers both instrumentation and services via our imaging platform, XerraTM, a high-resolution, high-sensitivity preclinical imaging tool designed to advance discoveries in biological and drug research. CFT spans many application areas including:
- Drug Discovery and Delivery
- Oncology and Immunotherapy
- Gene and Cell Therapy
Drug Discovery & Delivery
CFT is an important tool to monitor drug distribution, pharmacokinetic, and pharmacodynamic studies.
Oncology & Immunotherapy
CFT can play a key role for studying tumor models including microenvironments, tumor heterogeneity, metastatic spread, and expression of specific biomarkers.
Gene & Cell Therapy
(CFT) and Xerra™, a 3D imaging technology allows whole-body detection and visualization of vector biodistribution and vector-mediated gene expression, in high resolution and with high sensitivity.
The 3D CFT maps of fluorescence reporters can aid in visualization of cell tracking, drug delivery, and pharmacodynamics in the brain.