Drug discovery & delivery
Monitor on- and off-target expression with resolution and sensitivity.
CFT for drug discovery and delivery
Cryo-Fluorescence Tomography (CFT) is an ex vivo, volumetric tissue imaging technique used to monitor the pharmacokinetics and pharmacodynamics (PK/PD) of drugs and delivery vehicles with high resolution and sensitivity. Images of the anatomy (white light) are acquired alongside fluorescence images that are displayed in a 3D visualization of the drug and/or delivery vehicle biodistribution.
EMIT Imaging's visualization tools make CFT data easier to explore and collaborate on, with a full range of options to fit different user types and use cases.
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AAV-mediated protein expression
Findings: CFT uniquely achieves the required combination of resolution and sensitivity in a whole animal.
Visualization of cell intake
Findings: CFT was used to visualize labeled cell intake into tissue.
CFT application in large animal tissue
Findings: Because Xerra works in large formats, CFT has strong applications for anatomical RGB white-light and fluorescence imaging in large animal tissue, including NHP, bovine, porcine, and more.
