Oncology & immunotherapy
Monitor whole-body tumor burden and spread with 3D, high-resolution CFT imaging.
CFT in oncology and immunotherapy research
Cryo-Fluorescence Tomography (CFT) and EMIT Imaging's flagship platform Xerra™ are powerful techniques for oncology and immunotherapy applications. CFT provides anatomical and 3D fluorescence images to help researchers discover more when studying tumor models including microenvironments, tumor heterogeneity, metastatic spread, and expression of specific biomarkers.
For metastatic tumor progression, CFT detects metastatic disease and provides high-resolution 3D molecular data of tumor burden and spread not typically visualized in other imaging modalities. In addition, CFT is used to evaluate tumor metabolism and cell biology in response to genetic manipulations, pharmacologic agents, and cancer chemotherapy drugs.
EMIT Imaging's visualization tools make CFT data easier to explore and collaborate on, with a full range of options to fit different user types and use cases.
Contact us to identify the best visualization tool for your team and receive a demo →
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Fibroblast-activation protein (FAP)
Findings: Data confirms drug preferential uptake in the tumor with minimal uptake in other organs and tissues.
Comparison of FLI and CFT
Findings: CFT shows high-resolution, 3D co-localization of tumor cells and drugs, complementing 2D in vivo imaging.
Comparison of BLI and CFT
Findings: The CFT image shows the primary tumor extent and heterogeneity as well as the metastatic lesions in the lungs.
Want to see how your own data could look? Explore the full range of CFT visualization solutions.
Explore Visualization SolutionsExplore the data yourself, right in your browser
Open the CD68-Cre macrophage reporter or the lung metastases dataset and page through slices, toggle fluorescence channels, and rotate the reconstructed volume. Nothing to download and nothing to install.