Publications

Cryo‑Fluorescence Tomography as a Tool for Visualizing Whole‑Body Inflammation Using Perfluorocarbon Nanoemulsion Tracers

Leach, B.I., Lister, D., Adams, S.R. et al. 

Mol Imaging Biol (2024). https://doi.org/10.1007/s11307-024-01926-w

Summary

MRI-Based Cell Tracking of OATP-Expressing Cell Transplants by Pre-Labeling with Gd-EOB-DTPA

Bhattacharyya, T., Mallett, C.L. & Shapiro, E.M.

Mol Imaging Biol 26, 233–239 (2024). https://doi.org/10.1007/s11307-024-01904-2

Summary

Intratumoral Biosynthesis of Gold Nanoclusters by Pancreatic Cancer to Overcome Delivery Barriers to Radiosensitization

Aaron S. Schwartz-Duval, Yuri Mackeyev, Iqbal Mahmud, Philip L. Lorenzi, Mihai Gagea, Sunil Krishnan, and Konstantin V. Sokolov

ACS Nano 2024, 18, 3, 1865–1881 (2024).  https://doi.org/10.1021/acsnano.3c04260

Summary

Characterization and biodistribution of under-employed gene therapy vector AAV7

Samantha A. Yost, Emre Firlar, Justin D. Glenn, Hayley B. Carroll, Steven Foltz, April R. Giles, Jenny M. Egley, Elad Firnberg, Sungyeon Cho, Trang Nguyen, William M. Henry, Karolina J. Janczura, Joseph Bruder, Ye Liu, Olivier Danos, Subha Karumuthil-Melethil, Sanjana Pannem, Valerie Yost, Yelena Engelson, Jason T. Kaelber, Hemi Dimant, Jared B. Smith, Andrew C. Mercer


 Journal of Virology. 2023 Oct 16; 10.1128/jvi.01163-23

Summary

Whole CNS 3D Cryo-Fluorescence Tomography Shows CSF Clearance along Nasal Lymphatics, Spinal Nerves, and Lumbar/Sacral Lymph Nodes

Stokes, C.; White, E.F.; Toddes, S.; Bens, N.; Kulkarni, P.; Ferris, C.F. 
 
J. Imaging 2023, 9, 45. https://doi.org/10.3390/jimaging9020045

Summary

Volumetric imaging of optically cleared and fluorescently labeled animal tissue (VIOLA) for quantifying the 3D biodistribution of nanoparticles at cellular resolution in tumor tissue

Nikolai Rakhilin, Bing Yang, Mary E. Spilker, Lisa K. Manzuk, Mary Katherine Montgomery, Eyoung Shin, Nadira Prashad, Jungyeon Hwang, Youngho Song, Frank Loganzo, Anand Giddabasappa, Sripad Ram,

Journal of Controlled Release, Volume 354, 2023, Pages 244-259, ISSN 0168-3659, https://doi.org/10.1016/j.jconrel.2022.12.060.

Summary

A Genetically Encoded Magnetic Resonance Imaging Reporter Enables Sensitive Detection and Tracking of Spontaneous Metastases in Deep Tissues

Nivin N. NyströmSean W. McRaeFrancisco M. MartinezJohn J. KellyTimothy J. SchollJohn A. Ronald; A 
Cancer Res 1 March 2023; 83 (5): 673–685. https://doi.org/10.1158/0008-5472.CAN-22-2770

Summary

Biodistribution and delivery of oligonucleotide therapeutics to the central nervous system: Advances, challenges, and future perspectives

Goto, A.Yamamoto, S., & Iwasaki, S. 
Biopharmaceutics and Drug Disposition44(1), 2647. 2023 https://doi.org/10.1002/bdd.2338

Summary

Preclinical characterization of novel radiolabeled and fluorescent-labeled Fibroblast Activation Protein (FAP)-targeting ligands using gamma counting, SPECT imaging and Cryo-Fluorescence Tomography (CFT)

Hesterman, Novicki, White, Stokes, Cordova, Toddes, Silva, Burke, Domarkas, Wright, Archibald, Yost, Heimann, DiMagno, Hillier, Patel, Orcut, Amor, Tully, Babich, Hoppin

 

 EANM 2023

Summary

STING Agonist Delivery by Tumour-Penetrating PEG-Lipid Nanodiscs Primes Robust Anticancer Immunity

Eric L. Dane, Alexis Belessiotis-Richards, Coralie Backlund , Jianing Wang, Kousuke Hidaka, Lauren E. Milling, Sachin Bhagchandani, Mariane B. Melo, Shengwei Wu, Na Li, Nathan Donahue, Kaiyuan Ni , Leyuan Ma, Masanori Okaniwa , Molly M. Stevens , Alfredo Alexander-Katz, and Darrell J. Irvine

 

Nature Materials. 21, 710-720 (2022)

Summary

High-Contrast Detection of Somatostatin Receptor Subtype2 for Fluorescence-Guided Surgery

Servando Hernandez Vargas, Solmaz AghaAmiri, Sukhen C. Ghosh, Michael P. Luciano, Luis C. Borbon, Po Hien Ear, James R. Howe, Jennifer M. Bailey-Lundberg, Gregory D. Simonek, Daniel M. Halperin, Hop S. Tran Cao, Naruhiko Ikoma, Martin J. Schnermann, and Ali Azhdarinia

 

Mol. Pharmaceutics 2022, 19, 4241−4253

Summary

Microenvironment-triggered multimodal precision diagnostics

Liangliang Hao, Nazanin Rohani, Renee T. Zhao, Emilia M. Pulver, Howard Mak, Olivia J. Kelada, Henry Ko, Heather E. Fleming, Frank B. Gertler & Sangeeta N. Bhatia


Nature Materials. 20, 1440–1448 (2021).

Summary

Emergent Fluorous Molecules and Their Uses in Molecular Imaging

Chao Wang, Stephen R. Adams, and Eric T. Ahrens

 

Accounts of Chemical Research. 2021 Aug 3;54(15):3060-3070 

Summary

Immunotherapy-induced antibodies to endogenous retroviral envelope glycoprotein confer tumor protection in mice

Kang BH, Momin N, Moynihan KD, Silva M, Li Y, Irvine DJ, et al.

 

(2021) PLoS ONE 16(4): e0248903. https://doi.org/10.1371/journal.pone.0248903

Summary

Transcriptomic Analysis of Diffuse Intrinsic Pontine Glioma (DIPG) Identifies a Targetable ALDH-Positive Subset of Highly Tumorigenic Cancer Stem-like Cells

Rachel K. SurowiecSarah F. FerrisApril ApfelbaumCarlos EspinozaRanjit K. MehtaKaramoja MonchampVeerin R. SirihorachaiKaran BediMats LjungmanStefanie Galban

 

Mol Cancer Res 1 February 2021; 19 (2): 223–239. https://doi.org/10.1158/1541-7786.MCR-20-0464

Summary

Fluorescence-guided resection of tumors in mouse models of oral cancer

Demétrio de Souza França, P., Guru, N., Roberts, S. et al.

 

Sci Rep 10, 11175 (2020). https://doi.org/10.1038/s41598-020-67958-8

Summary

Fluorescence labeling of a NaV1.7-targeted peptide for near-infrared nerve visualization

Gonzales, J., Pirovano, G., Chow, C.Y. et al.

 

EJNMMI Res 10, 49 (2020). https://doi.org/10.1186/s13550-020-00630-4

Summary

Brain Pharmacology of Intrathecal Antisense Oligonucleotides Revealed Through Multimodal Imaging

Mazur C, Powers B, Zasadny K, Sullivan JM, Dimant H, Kamme F, Hesterman J, Matson J, Oestergaard M, Seaman M, Holt RW, Qutaish M, Polyak I, Coelho R, Gottumukkala V, Gaut CM, Berridge M, Albargothy NJ, Kelly L, Carare RO, Hoppin J, Kordasiewicz H, Swayze EE, Verma A

 

Journal of Clinical Investigation Insight. 2019 Oct 17;4(20)

Summary

Dynamic Dual-Isotope Molecular Imaging Elucidates Principles for Optimizing Intrathecal Drug Delivery

Wolf DA, Hesterman JY, Sullivan JM, Orcutt KD, Silva MD, Lobo M, Wellman T, Hoppin J, Verma A.

 

Journal of Clinical Investigation Insight. 2016 Feb 25;1(2)

Summary

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